Distance and Time
As compared to the regular routes between Mumbai and Pune (which are in the range of 120 to 160 kilometres long), this route, at a total distance of about 340-odd kilometres (plus the distance of any detours that you may take) is considerably longer.
It’s a very hectic one-day journey, so it might be more enjoyable to do this route over the course of a weekend. Several of the places along this route are weekend destinations in themselves (i.e. Igatpuri, Nashik and Bhandardara). So, a more interesting way to use this route might be to plan overnight stops at one or more of these places along the way and eventually return to Mumbai from Pune (or vice-versa) using the faster and “normal” expressway route.
Food is more easily available on the National Highways than on the State Highways. While the road to Igatpuri has several large restaurants and eateries, once you get off the main highways, your options become more limited and basic. There is a MTDC restaurant at Bhandardara, but I was told that food is available only between specific timings. If you’re particular about where and what you eat, it would be good to carry some food along. If food is a part of your adventure, you might actually enjoy the authentic food available in some of the dhabas in the rural areas.