284 Kms from Guanajuato
After exiting the airport I took a cab through one of the pre-paid taxi stands there (there might be cheaper options but I didn't want to waste the limited time I had to explore). I exchanged the USD at the airport, although, in hindsight, I think I'd have gotten a better rate at the ATMs. Me in Mexico City The taxi dropped me about 2 blocks from the hotel, it cost about 305 Pesos (~22 USD). I had booked a hotel close to Zocalo which is their main square. Think of it like the heart of the city; thousands of people throng this square during weekends and special occasions. It's the thriving spot of culture, politics, and all major events happening in the city. You'll find street performers, road side vendors, bargain gift shops, among others, at Zocalo. It also has the most important historic and architectural monuments of the city: The Metropolitan cathedral, National Palace (Palacio Nacional), Mueseo de bella arte, Palacio Postal, Angel de la independencia (the latter three are walk able distances away).
216 Kms from Guanajuato
There are a lot of things in Guadalajara, the second largest town of Mexico that makes it an interesting place to spend time in. It has the biggest market in Latin America – San Juan de Dios with three floors. I have met the nicest Mexican women here. It is one of the most traditional, religious and conservative cities in Mexico. It is not a colonial city like Guanajuato or San Miguel de Allende, but with many avenues, the best modern infrastructure possible. An interesting fact about Guadalaraja -at night, usually at 11pm, people gather on bicycles and take a different route every night around the city, go to the movies or theatre together. It is a fun city with lots of good things and good people.