From Kathmandu you take a cab to Pokhara from where Jomsom is 8 hours away. Then you trek up. Another way is from Pokhara fly to Jomsom and reaching mustang is comparatively nearby. If you plan for a bus ride from Pokhara reach bai I then another bus to ghasa then another bus to Jomsom. To explore on the trek here are some exclusive spots Syanboche village
Lo manthang
Dhamkar
Chhusang
Mukthimath temple
Chungsi cave
Luri Gumba and Chhoser.,