The cannabis sativa plant contains the cannabinoid CBN Distillate. Additionally, it can be created synthetically.
When THC deteriorates as a result of exposure to heat, air, and/or light, CBN develops. According to a manufacturer and developer of rare cannabinoids, "This is why larger quantities of CBN can be detected in aged, dried cannabis." The powerful euphoric effects linked to THC are not known to occur with CBN.
What's the difference between CBD and CBN?
One of the most well-known cannabinoids found in cannabis sativa plants is cannabidiol (CBD). Although it resembles CBN, CBD isn't made from THC; rather, it develops on its own in plants.
Compared to CBN, CBD has received more in-depth research in clinical settings and is more widely used in standard retail items. Numerous medicinal effects of CBD have been demonstrated by research; CBN Distillate is now unable to match that number.
Among its advantages are, but are not limited to:
Reducing the effects of sadness and anxiety symptoms
Reducing discomfort brought on by ailments like multiple sclerosis, cancer, and damaged nerves
Arthritic symptom reduction
Addressing the two uncommon kinds of epilepsy
Combining the treatment of opioid addiction with other measures
The endocannabinoid system of the body, which is involved in the functioning of the central nervous system and aids in the body's response to both internal and external stimuli, is where both CBN and CBD have a propensity to connect with CB2 receptors. Most commonly, CB2 receptors are connected to immune system control.
Possible advantages of CBN Distillate
Although there is a dearth of research on CBN Distillate, particularly in terms of human clinical trials, certain preclinical studies indicate the compound may have some medicinal potential.
Epidermolysis bullosa treatment
As a treatment for the rare illnesses known as epidermolysis bullosa, which cause the skin to blister readily, researchers are now studying CBN cream. InMed Pharmaceuticals discovered that its CBN cream "was well-tolerated on both normal, intact skin as well as on open wounds and caused no delay in wound healing" during the second stage of its clinical research.
According to Eric Hsu, senior vice president of pre-clinical research and development at InMed Pharmaceuticals, CBN Distillate may have anti-inflammatory properties that could be "helpful in healing chronic wounds when healing has been hindered by persistent inflammation."
Reduced Glaucoma Symptoms and Effects
According to research done by InMed Pharmaceuticals, CBN Distillate may be helpful in treating eye diseases including glaucoma, which affects the optic nerve in the back of the eye and results in blindness and visual loss. Glaucoma is known to be accompanied by high ocular pressure, and decreasing that pressure is a known method of slowing the disease.
According to an in vitro study conducted by InMed Pharmaceuticals, certain retinal cells treated with a topical CBN compound had a high rate of cell survival when subjected to high pressure situations. In these tests, CBN Distillate fared better than CBD and THC. CBN can also show neuroprotective properties, which means that it can guard the cells and structures of the nervous system by drastically lowering or preventing normal cell death.
Taking Care of Chronic Muscle Pain
CBN, CBD, and a combination of the two cannabinoids were proven to lessen muscular sensitivity in a 2019 study on rats. The researchers hypothesise that CBN may help treat chronic muscle pain disorders like fibromyalgia, which causes widespread pain throughout the body, and temporomandibular disorders, which cause pain in the jaw muscles, joints, and nerves. However, clinical studies are still needed to test this hypothesis.
CBN Distillate Risks and Potential Side Effects
Without extensive clinical research, it is challenging to pinpoint the precise effects of CBN Distillate on the human body. As a result, CBN has two potential risks: tiredness and sedation as well as a positive drug test result.
Sedation and Sleepiness
According to Laura Fuentes, a licenced compounding pharmacist and the chief officer of science and innovation for Green Roads, a manufacturer of CBD products, drowsiness is a potential adverse effect of CBN Distillate, particularly when taken with CBD.
Because of this, she advises against using CBN products throughout the workday. We will offer additional information about side effects and drug interactions when further study is conducted.
Having stated that, customers frequently use CBN products to aid in sleep and relaxation, and in these circumstances, the user may view these effects as potential advantages.
Positive result on a drug test
According to Mark Ratner, M.D., the chief science officer at Theralogix, a manufacturer of nutritional supplements, "there is evidence that use of CBN could unintentionally contribute to failed drug tests."
In two different drug tests, CBN caused positive results, according to at least one research. In one test, CBN even showed a "additive effect" with THC, effectively making THC more visible. Therefore, depending on the sensitivity of the drug test, even if you had virtually undetectable levels of THC in your system, the presence of CBN Distillate could skew your levels higher, resulting in a positive drug test.
How to Purchase CBN Products
If you choose to test a CBN product, you can probably discover a few choices from well-known CBD manufacturers. When purchasing cannabis products, confirm that the supplier:
Provides all of its products a certificate of analysis (COA). This paper should list the precise concentrations of different cannabinoids in the product as well as any mold, heavy metals, and pesticides that may be present.
Uses independent testing. To avoid conflicts of interest, prejudices, and inaccurate labeling, a corporation should send its products to a third-party laboratory for impartial testing. For more information, you may also check out independent labs.
Utilizing CBN
Before beginning to use CBN Distillate, speak with a medical expert, especially given the paucity of clinical trials.
Similar to CBD, CBN is available in a variety of forms, with oils, tinctures, candies, and capsules being the most popular. Additionally, CBD products including CBN are more prevalent than those that only include CBN.
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