You can do it, plan train journeys as Europe is well connected by rail network, start from Paris (3 days), proceed to Brussels (1 day), start for Switzerland (3 days) and last to Rome (3 days).
I was planning a similar trip last year. The main thing is to choose good hotels along the way. If it is an air travel, the main thing is to book all the airline tickets in advance. And you also need to take care of the transfer from the airport to the hotel. I was lucky, all the countries we planned to visit had offices of the one company https://limousine-service.com/. It's the kind of service I would safely recommend. Be sure to think about excursions to the places you want to see. You can also buy admission tickets to museums, galleries, and attractions in advance. If you do it in advance, it is much cheaper, plus you do not have to stand in line. Good luck.